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ACE2 expression (coronavirus binding)

Inner Circle Member Forum >> Vitamin D >> ACE2 expression (coronavirus binding)

RoniSue

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Posted: 3/18/2020 1:13:16 PM
 

Someone asked Mark Sisson what he thought about taking Vitamin D at this time. Here is what he said. I’m curious to see what Dr. Davis thinks about this angle. I had heard that some Inner Circle people are taking mega-doses for a few weeks to combat coronavirus. ???

“This is a tricky one. Normally, I’d say yes, it can’t hurt and very well might help. But with coronavirus, that gets more complicated. One thing vitamin D may have the potential to do is increase ACE2 expression, and ACE2 is the same receptor to which coronavirus binds. It’s the “entry point,” how it gets in and starts destroying cells. Organs with high rates of ACE2 receptors, like the lungs, appear to be the most affected organs.

If vitamin D increases ACE2 in the lungs, for example, that could leave you more open to infection. I certainly would avoid “megadoses” of vitamin D. If you take it, do something like 1000 IUs max, or get it through food (salmon, sardines, pastured eggs, mushrooms) or cod liver oil.”

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Bob Niland

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Posted: 3/18/2020 1:59:57 PM
Edited: 3/18/2020 3:38:45 PM (1)
 
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Kathy in OK

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Posted: 3/18/2020 3:35:49 PM
 
I think Kendrick’s latest  also addressed this.

https://drmalcolmkendrick.org/
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Ian989

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Posted: 3/18/2020 11:21:58 PM
 
How do we know base line doses (through food or sunshine) couldn’t do the same though?


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Bob Niland

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Posted: 3/19/2020 11:32:12 AM
Edited: 3/19/2020 12:30:51 PM (5)
 
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Ian989

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Posted: 3/19/2020 3:23:17 PM
 
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RoniSue

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Posted: 3/20/2020 2:09:49 PM
 
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Dr. Davis

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Posted: 3/20/2020 3:54:01 PM
 
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Bob Niland

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Posted: 3/20/2020 6:48:28 PM
 
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Bob Niland

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Posted: 3/23/2020 8:50:28 AM
Edited: 3/23/2020 10:34:16 AM (1)
 
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Boo

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Posted: 3/23/2020 11:34:20 AM
 
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Posted: 3/23/2020 11:55:01 AM
 
Is it okay for people that take blood thinning medications to take NAC?


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Bob Niland

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Posted: 3/23/2020 11:59:20 AM
 
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Posted: 3/27/2020 10:28:05 AM
 
I got freaked by Kresser after I had ordered high dose D and propolis. Both he retracted from recommending. Received lots of advice from all directions to keep D under 400.  So, like ibuprofen, will err on side of caution. 


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