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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

Member Forum >> Coronary Disease & Cholesterol Protocol >> Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

Bob Niland

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Posted: 4/7/2016 5:33:51 PM
Edited: 4/8/2016 10:05:05 AM (5)
 

Paper (pay-walled) here:
STM: Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

Press story here:
ars: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

University press release here:
Uni Bonn: Ring-shaped sugar helps in cases of artherosclerosis

The press release has more useful detail than the ars story (which includes some dumb lipid dogma instead).

Cyclodextrin is a ring sugar already used as a food additive, and presumably GRAS, so expect a big uptick in your 2-hydroxypropyl-ß-cyclodextrin stock investments, and lots of N=1 experiments. Since this stuff is not patentable at this point, it's hard to speculate on what CVD trials might be undertaken.

It does appear that oral ingestion doesn't work - it needs to be IV, which probably explains why nobody stumbled across this effect before.

I haven't seriously dug into this yet, but I'm already wondering if the claimed plaque reversal is soft or calcified. There's also the question of how quickly the reversal works, and whether there's risk of triggering events. This might actually be the rare case of a pay-walled paper worth paying the ransom on.

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Bob Niland [disclosures] [topics]

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Dr. Davis

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Posted: 4/10/2016 12:58:33 PM
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Malcolm

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Posted: 4/10/2016 6:28:01 PM
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Bob Niland

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Posted: 4/10/2016 7:30:16 PM
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ptheut

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Posted: 4/11/2016 9:45:44 AM
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Bob Niland

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Posted: 4/11/2016 11:19:17 AM
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Bob Niland

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Posted: 4/17/2016 8:33:56 AM
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Boo

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Posted: 4/17/2016 1:28:27 PM
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Pek

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Posted: 3/10/2021 5:33:53 PM
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I noticed that LEF is no longer offering this product.

Did anyone participating in this thread ever try this?  
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Lucky Lime

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Posted: 3/10/2021 5:49:24 PM
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years ago, I was giving some type of medication that doesn’t go through the liver, but tries to lower cholesterol into the intestines... I wish I remember the name ...I remember it didn’t work.


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Pek

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Posted: 3/15/2021 11:44:50 AM
Edited: 3/15/2021 11:48:01 AM (1)
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docmaas

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Posted: 3/15/2021 5:23:09 PM
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Pek

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Posted: 3/15/2021 7:53:11 PM
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what? ??... just kidding 
;)

 

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