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Posted: 6/26/2014 12:18:24 AM
- Omega-3 Fatty Acids in the Management of Hypertriglyceridemia: New Findings and Formulations - Continuing Medical Education (CME):Princeton Media Associates, exp. 10/29/06 - "To lower TG levels, the dose of omega-3 therapy is ~4 g of EPA + DHA per day"
- Omega-3 Fatty Acids: Recommendations for Therapeutics and Prevention - Medscape, exp. 10/19/06 -"Studies support low DHA as a risk factor for dementia. Low total n-3 fatty acids levels, EPA and DHA associate with greater risk of CVD, dietary intake and/or supplementation is supported as a secondary or tertiary prevention measure. Omega-3 fatty acids also help to prevent type 2 diabetes and the metabolic syndrome, two common precursors to CVD. There is some support for schizophrenia, depressive or aggressive disorders; however, large multi-center clinical trials have yet to be conducted. The anti-inflammatory properties of n-3 fatty acids are helpful in decreasing symptoms of rheumatoid arthritis and may possibly increase remission length in Crohn's patients"
- Omega 3: Implications in human health and disease - PowerPak (CME course), exp. 8/1/03 - "On average, our society consumes around 35% of its caloric intake from fat, mainly as vegetable oil. The omega 6 LA comprises 7% to 9% of our daily caloric intake, while the omega 3 LNA makes up about 0.7% of energy. It is therefore estimated that the dietary ratio of LA to LNA ranges from 10 to 20:1, at which level the metabolism of LNA is strongly suppressed.2,25 Again, this is far more than the recommended ratio of 2.3:1" - See Mega Twin EPA at Amazon.com.
- An Evidence-Based Medicine Approach to the Appropriate Selection of Supplementation with Omega-3 Fatty - PowerPak.com, 6/1/07 - "Fish oils EPA and DHA appear to result in different physiologic effects than their precursor, the plant-derived ALA.12-14 Biosynthesis of EPA or DHA from ALA is limited. Although dietary consumption of ALA alone will prevent EFA deficiency, emerging scientific evidence indicates that for optimum health or body function, the fish oils EPA and DHA should also be ingested regularly, either from dietary or supplement sources. Use of ALA supplementation alone, even with high dose or long-term consumption, does not result in lowered triglyceride concentrations seen with EPA or DHA, nor does it demonstrate similar in vitro susceptibility to oxidation of LDL cholesterol"
- The Heart-Healthy Benifits of Omega-3 Fatty Acids - John Hopkins University School of Medicine, 6/05 - "Fish-oil supplements appear to have much lower levels of toxins than fish. In a study of 5 over the-counter fish-oil preparations, levels of PCBs and organochlorines were below the detectable limit in all of the supplements ... Because consumption of this amount of fish in secondary prevention is difficult for most individuals, dietary supplementation is generally needed and should be recommended. The dose in secondary prevention should be at least 875 mg of EPA + DHA per day. This dose can generally be obtained by taking 2 capsules of concentrated fish oils (at least 50% EPA + DHA) per day. For example, such a preparation would contain 500 mg of EPA + DHA per each 1000-mg fish-oil capsule"
- Omega 3: Implications in Human Health and Disease - PowerPak.com - "It should be noted, however, that flaxseed or flaxseed oil does not contain EPA or DHA. Thus flaxseed and fish oil are not interchangeable sources of omega 3 fatty acids per se" - I believe the same holds true for canola oil - Ben
- Omega 3: Implications in Human Health and Disease -PowerPak.com -"The omega 6 LA comprises 7% to 9% of our daily caloric intake, while the omega 3 LNA makes up about 0.7% of energy. It is therefore estimated that the dietary ratio of LA to LNA ranges from 10 to 20:1, at which level the metabolism of LNA is strongly suppressed. Again, this is far more than the recommended ratio of 2.3:1 ... From an evolutionary perspective, a significant change in the diet has occurred in a very short time. The diet of our ancestors in the Paleolithic period (400,000 to 45,000 years ago) was lower in fat and balanced in omega 6 and omega 3—a ratio of 1:1, or 10- to 20-fold lower than today's standard."
News & Research:
- Omega-3 inhibits blood vessel growth in age-related macular degeneration - Science Daily, 6/17/14 - "Age-related macular degeneration (AMD), which is characterized by choroidal neovascularization (CNV), or blood vessel growth, is the primary cause of blindness in elderly individuals of industrialized countries ... the omega (ω)-3 long-chain polyunsaturated fatty acids (LCPUFAs), DHA and EPA, and their specific bioactive products derived from the cytochrome P450 (CYP) pathway, can influence choroidal neovascularization (CNV) and vascular leakage by modulating micro-environmental immune cell recruitment to the site of these lesions ... Given the prevalence of neovascular eye disease, the potential impact of this study is highly significant. We have identified unique endogenous lipid biometabolites that are able to inhibit pathologic retinal angiogenesis, a major driver of vision loss worldwide"- See fish oil supplements at Amazon.com.
- Diet Rich in Polyphenols Improves Glucose Metabolism - Medscape, 6/4/14 - "they randomized 45 patients to one of four diets: a standard control diet that was low in omega-3 fatty acids and polyphenols, a diet rich in omega-3 fatty acids, a diet rich in polyphenols, and a diet that included omega-3 fatty acids and polyphenols. All patients were overweight or obese, with a body-mass index > 30 ... Although individuals lost more weight on the eight-week omega-3-fatty-acid–enriched diet, there were significantly greater improvements in plasma glucose and plasma insulin levels with the polyphenol-enriched diet during an oral glucose tolerance test. The improvement in glucose metabolism was observed only in those who consumed the polyphenol-enriched diet ... this particular mechanism of action with polyphenols is similar to drugs used in the treatment of diabetes. However, rather than wait until the patient is diagnosed with the metabolic disease, a diet rich in polyphenols could be used as a preventive strategy"
- Diet can predict cognitive decline, researchers say - Science Daily, 4/27/14 -"What is the takeaway from this research? There is growing evidence that very long chain omega-3 fatty acids are beneficial for maintaining cognitive health, and many Americans do not have an adequate intake of these nutrients" - See fish oil supplements at Amazon.com.
- Fatty-Fish Consumption Alters HDL-Particle Profile - Medscape, 3/7/14 - "Although total-, LDL-, and HDL-cholesterol levels did not change, for those who consumed this healthy diet rich in polyunsaturated fatty acids, the intake of fish was strongly correlated with an increased concentration of large HDL particles, including an increase in the average diameter of HDL particles and an increase in the concentrations of large HDL lipid components ... The changes that we saw in large HDL particles could be related to those parameters that are functionally related to reverse cholesterol transport ... Thus, our findings could partly explain the known protective effects of fish consumption against atherosclerosis"
- Fish Oil Might Guard Against Loss of Brain Cells - WebMD, 1/22/14 -"The more you consume the omega-3 fatty acids found in fish oils, the less likely you are to lose as many precious brain cells as you age ... the researchers tested levels of omega-3 fatty acids in the red blood cells of more than 1,000 older women. Eight years later, the women had MRI scans that measured their brain volumes. At the time of the scans, the women were an average of 78 years old ... Participants whose omega-3 levels were twice as high had a 0.7 percent higher brain volume ... The results suggest that the effect on brain volume is the equivalent of delaying the normal loss of brain cells that comes with aging by one to two years" - [Medscape] - See fish oil supplements at Amazon.com.
- Fish derived serum omega-3 fatty acids help reduce risk of type 2 diabetes - Science Daily, 1/14/14 - "Ongoing at the University of Eastern Finland, the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) determined the serum omega-3 fatty acid concentrations of 2,212 men between 42 and 60 years of age at the onset of the study, in 1984-1989 ... follow-up of 19.3 years ... The risk of men in the highest serum omega-3 fatty acid concentration quarter to develop type 2 diabetes was 33% lower than the risk of men in the lowest quarter" - See fish oil supplements at Amazon.com.
- Omega-3 Dietary Supplements Pass Blood-Brain Barrier - Science Daily, 12/4/13 -"omega-3 fatty acids in dietary supplements can cross the blood brain barrier in people with Alzheimer's disease ... The findings are presented in the Journal of Internal Medicine, and strengthen the evidence that omega-3 may benefit certain forms of this seriously debilitating disease ... Thirty-three patients participated in the study, 18 of whom received a daily omega-3 supplement and 15 a placebo for six months. The results show that the first group had higher levels of both DHA and eicosapentaenoic acid (EPA, another omega-3 fatty acid) in their cerebrospinal fluid (which surrounds the CNS) and blood. No such change was seen in the placebo group ... Moreover, they also found that levels of DHA correlated directly with the degree of change in Alzheimer's disease and inflammatory markers in the cerebrospinal fluid"
- Low-fat fish oil changes cancer tissue in prostate cancer, study shows - Science Daily, 11/18/13 - "Men with prostate cancer who ate a low-fat diet and took fish oil supplements had lower levels of pro-inflammatory substances in their blood and a lower cell cycle progression score, a measure used to predict cancer recurrence ... lowering the cell cycle progression (CCP) score may help prevent prostate cancers from becoming more aggressive ... The Western diet consisted of 40 percent of calories from fat, generally equivalent to what many Americans consume today .... The low-fat diet consisted of 15 percent of calories from fat. Additionally, the men on this diet took five grams of fish oil per day in five capsules, three with breakfast and two with dinner, to provide omega-3 fatty acids"
- High serum fatty acid protects against brain abnormalities - Science Daily, 10/17/13 - "3,660 people aged 65 and older underwent brain scans to detect so called silent brain infarcts, or small lesions in the brain that can cause loss of thinking skills, dementia and stroke. Scans were performed again five years later on 2,313 of the participants ... silent brain infarcts, which are only detected by brain scans, are found in about 20% of otherwise healthy elderly people ... those who had high long-chain omega-3 polyunsaturated fatty acid content in blood had about 40% lower risk of having small brain infarcts compared to those with low content of these fatty acids in blood ... people who had high long-chain omega-3 polyunsaturated fatty acid content in blood also had fewer changes in the white matter in their brains"
- Diet during pregnancy and early life may affect children's behavior and intelligence - Science Daily, 9/13/13 - "Blood samples were taken from 493 schoolchildren, aged between seven and nine years, from 74 mainstream schools in Oxfordshire. All of the children were thought to have below-average reading skills ... Analyses of their blood samples showed that, on average, just under two per cent of the children's total blood fatty acids were Omega-3 DHA (Docosahexaenoic acid) and 0.5 per cent were Omega-3 EPA (Eicosapentaenoic acid), with a total of 2.45 per cent for these long-chain Omega-3 combined. This is below the minimum of 4 per cent recommended by leading scientists to maintain cardiovascular health in adults, with 8-12 per cent regarded as optimal for a healthy heart ... levels of Omega-3 fatty acids in the blood significantly predicted a child's behaviour and ability to learn. Higher levels of Omega-3 in the blood, and DHA in particular, were associated with better reading and memory, as well as with fewer behaviour problems as rated by parents and teachers"
- Fatty acids could aid cancer prevention and treatment - Science Daily, 8/1/13 -"new research from scientists at Queen Mary, University of London ... In vitro tests showed omega-3 fatty acids induced cell death in malignant and pre-malignant cells at doses which did not affect normal cells, suggesting they have the potential to be used in both the treatment and prevention of certain skin and oral cancers"
- Diets lacking omega-3s lead to anxiety, hyperactivity in teens: Generational omega-3 deficiencies have worsening effects over time - Science Daily, 7/29/13 -"in a rodent model second-generation deficiencies of omega-3s caused elevated states of anxiety and hyperactivity in adolescents and affected the teens' memory and cognition ... this dietary deficiency can compromise the behavioral health of adolescents, not only because their diet is deficient but because their parents' diet was deficient as well. This is of particular concern because adolescence is a very vulnerable time for developing psychiatric disorders including schizophrenia and addiction."Diets lacking omega-3 fatty acids -- found in foods like wild fish, eggs, and grass-fed livestock -- can have worsened effects over consecutive generations, especially affecting teens"
- Fish Oil's Link to Prostate Cancer Unproven - Medscape, 7/26/13 - "The bottom line is that we cannot determine from this study design whether the intake of omega-3 fatty acids will cause prostate cancer and raise a man's risk for high-grade disease. The media has taken this and sensationalized the risk associated with omega-3 fatty acid intake"
- Low Omega-3 in Kids Linked to Behavior, Cognitive Deficits - Medscape, 7/23/13 -"This study formed the screening stage of a previously published randomized controlled intervention study that included 362 healthy children aged 7 to 9 years from primary schools in Oxfordshire, a large county in the UK, who had low reading scores. The DOLAB study reported that supplementation with 600 mg DHA daily for 16 weeks improved reading and behavior in children with the lowest 20% of reading scores ... The study showed that reading scores were significantly and positively associated with the omega-3 fatty acids DHA (P < .003), docosapentaenoic acid (DPA; P < .04), eicosapentaenoic acid (EPA; P < .005), and the omega-3 index (EPA+DHA; P < .04). Total omega-6 fatty acids also showed a positive correlation with reading ... Results were similar for working memory. Scores for Recall of Digits Forward were significantly and positively associated with DHA (P < .003), DPA (P < .04), EPA (P < .005), the omega-3 index (P < .001), and total omega-3 (P < .004)"
- How a SELECTed Bad Study Became Big News - Dr. Michael Murray, 7/12/13 -"This study is not consistent with other studies (discussed below) ... There is no evidence that anybody in this study took fish oil supplements or even ate fish ... In usual circumstances, plasma levels of EPA and DHA reflect very recent intake and are considered a poor biomarker of long-term omega-3 intake ... Patients with prostate cancer may have only recently increased their fish and/or fish oil consumption ... Fish and fish oil ingestion produces a big rise in plasma omega-3 levels in about 4.5 hours and washes out around 48 hours ... The data may reflect cancer activity rather than a causative association. Without dietary history or documentation of fish oil use there is no way of knowing"
- Experts slam omega-3 link to prostate cancer as 'scaremongering' - Nutra USA, 7/12/13 - "if the findings of the new study were true, "then prostate cancer would be rampant in any country with high seafood consumption (Scandinavia, Japan etc) and conversely, low level consumption should be protective"
- Specific Fish Oils May Protect Against Breast Cancer - Medscape, 6/27/13 - "The consumption of higher levels of dietary marine n-3 polyunsaturated fatty acids (PUFAs) is associated with a 14% lower risk for breast cancer than lower levels of consumption ... They found that marine n-3 PUFAs were associated with a 14% reduction in the risk for breast cancer (relative risk [RR] for highest vs lowest intake, 0.86) ... no significant association was observed for exposure to alpha linolenic acid (ALA), which is contained in some nuts and in vegetable oils. About half of the studies in the meta-analysis contained data on ALA. Both ALA and n-3 PUFAs are types of omega-3 fatty acids" - [Science Daily] - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Could a Diet High in Fish and Flax Help Prevent Broken Hips? - Science Daily, 6/27/13 - "The study showed that higher levels of omega-3 fatty acids from both plant and fish sources in those blood cells were associated with a lower likelihood of having fractured a hip ... The study also showed that as the ratio of omega-6 fatty acids to omega-3s increased, so did the risk for hip fracture ... Inflammation is associated with an increased risk of bone loss and fractures, and omega-3 fatty acids are believed to reduce inflammation ... omega-3 fatty acids have anti-inflammatory properties and omega-6 fatty acids seem to have both anti- and pro-inflammatory effects ... women who had the highest ratio of omega-6 to omega-3 fatty acids had nearly twice the risk of hip fractures compared to women with the lowest ratios. The current typical American diet contains between 15 and 17 times more omega-6 than omega-3, a ratio that previous research has suggested should be lowered to 4-to-1, or even 2-to-1, by increasing omega-3s, to improve overall health. The primary omega-6 fatty acid in the diet is linoleic acid, which composes about 99 percent of Americans' omega-6 intake and is found in corn, soybean, safflower and sunflower oils"
- Marine n-3 Polyunsaturated Fatty Acids - Medscape, 6/11/13 - "Sarcopenia is the age-related loss of muscle mass that results in a reduction in skeletal muscle function, quality of life and an increased risk of falls. Older muscle has an 'anabolic resistance' to both nutrients and exercise, with the precise underlying mechanism still to be elucidated. The n-3 polyunsaturated fatty acids found in fish oil can be incorporated into the membranes of skeletal muscles, where they may have anti-inflammatory effects. This alteration in muscle membrane fatty acid composition may have anabolic effects in aging muscle and, thus, be useful in the treatment of sarcopenia ... The current data presented suggest that n-3 PUFAs may be of benefit in the treatment of sarcopenia"
- Omega-3 fatty acids may help heal a broken heart - Science Daily, 5/30/13 -"The potency of these compounds corresponds to concentrations that have been measured in the blood of human subjects taking high dose fish oil supplements for short periods of time. In rabbits, researchers treated the artery with RvD at the time of the balloon angioplasty procedure by infusing the drug directly into the vessel, and found that this one-time treatment reduced inflammation and subsequent scarring of the vessel after one month"
- Fish Oil Supplements May Help Fight Against Type 2 Diabetes - Science Daily, 5/22/13 - "Fish oil supplements, also called omega 3 fatty acid capsules, raise levels of adiponectin in the bloodstream. Adiponectin is an important hormone that has beneficial effects on metabolic processes like glucose regulation and the modulation of inflammation. In long-term human studies, higher levels of adiponectin are associated with lower risks of type 2 diabetes and coronary heart disease ... The meta-analysis reviewed and analyzed results from 14 randomized, placebo-controlled clinical trials"
- Fish oil may help the heart beat mental stress - Science Daily, 5/22/13 -"volunteers who took fish oil supplements for several weeks had a blunted response to mental stress in several measurements of cardiovascular health, including heart rate and muscle sympathetic nerve activity (MSNA), part of the "fight or flight" response, compared to volunteers who took olive oil instead. The results may explain why taking fish oil could be beneficial to the heart and might eventually help doctors prevent heart disease in select populations"
- Fish oil may stall effects of junk food on brain - Science Daily, 5/14/13 -"high-fat diets could disrupt neurogenesis, a process that generates new nerve cells, but diets rich in omega-3s could prevent these negative effects by stimulating the area of the brain that control feeding, learning and memory ... Excessive intake of certain macronutrients, the refined sugars and saturated fats found in junk food, can lead to weight gain, disrupt metabolism and even affect mental processing ... These changes can be seen in the brain's structure, including its ability to generate new nerve cells, potentially linking obesity to neurodegenerative diseases ... omega-3 fish oils can reverse or even prevent these effects ... omega-3s restore normal function by interfering with the production of these inflammatory molecules, suppressing triglycerides, and returning these nerve growth factors to normal ... Fish oils don't appear to have a direct impact on weight loss, but they may take the brakes off the detrimental effects of some of the processes triggered in the brain by high-fat diets. They seem to mimic the effects of calorie restrictive diets and including more oily fish or fish oil supplements in our diets could certainly be a positive step forward for those wanting to improve their general health"
- Eating fish associated with lower risk of dying among older adults: Risk of dying from heart disease significantly lowered - Science Daily, 4/1/13 -"Older adults who have higher blood levels of omega-3 fatty acids -- found in fatty fish and seafood -- may be able to lower their overall mortality risk by as much as 27% and their mortality risk from heart disease by about 35% ... older adults who had the highest blood levels of the fatty acids found in fish lived, on average, 2.2 years longer than those with lower levels ... The researchers examined 16 years of data from about 2,700 U.S. adults aged 65 or older who participated in the Cardiovascular Health Study (CHS), a long-term study supported by the National Heart, Lung, and Blood Institute ... One type in particular -- docosahexaenoic acid, or DHA -- was most strongly related to lower risk of coronary heart disease (CHD) death (40% lower risk), especially CHD death due to arrhythmias (electrical disturbances of the heart rhythm) (45% lower risk). Of the other blood fatty acids measured -- eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA) -- DPA was most strongly associated with lower risk of stroke death, and EPA most strongly linked with lower risk of nonfatal heart attack"
- High Intake of Dietary Long-Chain ω-3 Fatty Acids Is Associated With Lower Blood Pressure in Children Born With Low Birth Weight: NHANES 2003-2008 - Hypertension. 2013 Mar 4 - "Reduced fetal growth is associated with increased systolic blood pressure ... In the 354 participants with reduced birth weight, when compared with children with the lowest tertile of intake, those who had the highest tertile of dietary eicosapentaenoic acid and docosahexaenoic acid intake had significantly lower systolic blood pressure (-4.9 mm Hg [95% confidence interval, -9.7 to -0.1]) and pulse pressure (-7.7 mm Hg [95% confidence interval, -15.0 to -0.4])" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Taking omega-3 supplements may help prevent skin cancer, new study finds - Science Daily, 2/26/13 - "the study analysed the effect of taking omega-3 on 79 healthy volunteers ... taking a regular dose of fish oils boosted skin immunity to sunlight. Specifically, it also reduced sunlight-induced suppression of the immune system, known as immunosuppression, which affects the body's ability to fight skin cancer and infection ... it was the first time the research had been carried out on humans"
- Omega-3s inhibit breast cancer tumor growth, study finds - Science Daily, 2/21/13 -"A lifelong diet rich in omega-3 fatty acids can inhibit growth of breast cancer tumours by 30 per cent ... the researchers created a novel transgenic mouse that both produces omega-3 fatty acids and develops aggressive mammary tumours. The team compared those animals to mice genetically engineered only to develop the same tumours ... Mice producing omega-3s developed only two-thirds as many tumours -- and tumours were also 30-per-cent smaller -- as compared to the control mice"
- Fish oil may protect dialysis patients from sudden cardiac death - Science Daily, 2/6/13 - "We found that higher levels of omega-3 fatty acids in the blood of patients who were just starting hemodialysis were very strongly associated with a lower risk of sudden cardiac death over the first year of their treatment ... The five-year survival rate for patients on hemodialysis is 35 percent, with the risk of death highest in the first few months of starting treatment. The most common cause of death in these patients is sudden cardiac death, which accounts for about one out of every four deaths"
- Omega-3-Rich Ground Beef Available Soon - Science Daily, 2/4/13 -"The U.S. currently does not have a recommended daily intake of omega-3s, though many doctors and nutritionists recommend between 1,200-1,600 milligrams daily ... A quarter-pound hamburger made of the enriched ground beef has 200 milligrams of omega-3s" - See Mega Twin EPA at Amazon.com which has 765 milligrams of omega-3 in one capsule. So you'd have to eat 3.825 hamburgers to get the omega-3 in one capsule. At 330 calories per hamburger, that's 1262 calories compared to 10 calories for the capsule.
- Limiting Polyunsaturated Fatty Acid Levels in Pregnancy May Influence Body Fat of Children - Science Daily, 1/10/13 - "mothers who have higher levels of n-6 polyunsaturated fatty acids (PUFAs), which are found in cooking oils and nuts, during pregnancy have fatter children ... assessed the fat and muscle mass of 293 boys and girls at four and six years, who are part of the Southampton Women's Survey (SWS), a large prospective mother-offspring cohort ... the higher the level of n-3 the less fat and more muscle and bone in the baby ... This could suggest that a pregnancy supplementation strategy would be beneficial"
- Association Between use of Specialty Dietary Supplements and C-Reactive Protein Concentrations - Medscape, 12/28/12 - "In summary, this study adds support to laboratory research and to some human studies which suggest that glucosamine, chondroitin, and fish oil may reduce systemic inflammation. In doing so, this study adds biologic plausibility to previous studies which have shown beneficial effects of these supplements on chronic diseases. Given the number of diseases with which inflammation is associated, such as cancer and cardiovascular disease, there is a need to find safe and effective ways to reduce inflammation. Research suggests that these 3 supplements have excellent safety profiles, [88–92] supporting their potential role in disease prevention"- Seeglucosamine products at Amazon.com,chondroitin sulfate at Amazon.com, Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Glucosamine, Chondroitin, Fish Oil May Reduce Inflammation - Medscape, 11/27/12 -"Inflammation is now recognized as a factor in cancer and cardiovascular disease as well as many rheumatoid diseases ... the researchers found hs-CRP reductions of 17% (95% confidence interval [CI], 7% - 26%) with glucosamine, 22% (95% CI, 8% - 33%) with chondroitin, and 16% (95% CI, 0.3% - 29%) with fish oil compared with participants who did not take the supplements"
- Eating more fish could reduce postpartum depression - Science Daily, 11/15/12 -"Low levels of omega-3 may be behind postpartum depression ... Because omega-3 is transferred from the mother to her fetus and later to her breastfeeding infant, maternal omega-3 levels decrease during pregnancy, and remain lowered for at least six-weeks following the birth" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Omega-3 intake heightens working memory in healthy young adults - Science Daily, 10/25/12 - "In the first study of its kind, researchers at the University of Pittsburgh have determined that healthy young adults ages 18-25 can improve their working memory even further by increasing their Omega-3 fatty acid intake ... After six months of taking Lovaza -- an Omega-3 supplement approved by the Federal Drug Administration -- the participants were asked to complete this series of outpatient procedures again. It was during this last stage, during the working memory test and blood sampling, that the improved working memory of this population was revealed" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com and probiotic products at Amazon.com.
- New link between high-fat 'Western' diet and atherosclerosis identified - Science Daily, 10/8/12 - "endothelial lipase (EL), an enzyme associated with the development of atherosclerosis ... In the current study, a strain of mice susceptible to atherosclerosis was fed a normal diet enriched with either palmitic acid (a common saturated fat) or eicosapentaenoic acid (an omega-3 fatty acid, or polyunsaturated fat, found in fish oil, among other foods). After 12 weeks, the mice's aortas were examined for changes in the expression of EL and inflammatory factors. Aortas of mice fed the saturated fat diet showed a significant increase in EL and detrimental changes in inflammatory factors, while those of mice fed the polyunsaturated fat diet showed a significant decrease in EL and beneficial changes in inflammatory factors ... when the macrophages were given rosiglitazone, the expression of EL increased markedly. The addition of omega-3 fatty acids to the cells blocked this increase. "This would suggest that besides raising LDL cholesterol levels, rosiglitazone can raise the risk of cardiovascular disease by increasing EL,""
- Prenatal mercury exposure may be linked to risk of ADHD-related behaviors; Fish consumption may be linked to lower risk - Science Daily, 10/8/12 -"Nonoccupational methylmercury exposure comes primarily from eating fish, and the U.S. Environmental Protection Agency and the U.S. Food and Drug Administration have recommended pregnant women limit their total fish intake to no more than two, six-ounce servings per week. However, fish is also a source of nutrients, such as omega-3 fatty acids, which have been shown to benefit brain development, potentially confounding mercury-related risk estimates ... analyzed data from the New Bedford birth cohort, a group of infants born between 1993 and 1998, to investigate the association of peripartum maternal hair mercury levels (n=421) and prenatal fish intake (n=515) with ADHD-related behaviors at age 8 years ... In this population-based prospective cohort study, hair mercury levels were consistently associated with ADHD-related behaviors, including inattention and hyperactivity/impulsivity. We also found that higher prenatal fish consumption was protective for these behaviors"
- Omega-3 supplements may slow a biological effect of aging - Science Daily, 10/1/12 -"In the study, lengthening of telomeres in immune system cells was more prevalent in people who substantially improved the ratio of omega-3s to other fatty acids in their diet ... Omega-3 supplementation also reduced oxidative stress, caused by excessive free radicals in the blood, by about 15 percent compared to effects seen in the placebo group ... Study participants took either 2.5 grams or 1.25 grams of active omega-3 polyunsaturated fatty acids ... The supplements were calibrated to contain a ratio of the two cold-water fish oil fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), of seven to one ... the typical American diet tends to be heavy on omega-6 fatty acids and comparatively low in omega-3s that are naturally found in cold-water fish such as salmon and tuna. While the ratio of omega-6 to omega-3 fatty acids averages about 15-to-1, researchers tend to agree that for maximum benefit, this ratio should be lowered to 4-to-1, or even 2-to-1 ... when the researchers analyzed the participants' omega-6 to omega-3 ratio in relationship to telomere lengthening, a lower ratio was clearly associated with lengthened telomeres ... omega-3 supplements lowered IL-6 by 10 to 12 percent, depending on the dose. By comparison, those taking a placebo saw an overall 36 percent increase in IL-6 by the end of the study ... This finding strongly suggests that inflammation is what's driving the changes in the telomeres"
- Omega-3 lowers inflammation in overweight older adults - Science Daily, 6/21/12 -"Chronic inflammation is linked to numerous conditions, including coronary heart disease, Type 2 diabetes, arthritis and Alzheimer's disease, as well as the frailty and functional decline that can accompany aging ... Participants received either a placebo or one of two different doses of omega-3 fatty acids -- either 2.5 grams or 1.25 grams per day ... After four months, participants who had taken the omega-3 supplements had significantly lower levels in their blood of two proteins that are markers of inflammation, also called pro-inflammatory cytokines. The low-dose group showed an average 10 percent decrease in the cytokine interleukin-6 (IL-6), and the high-dose group's overall IL-6 dropped by 12 percent. In comparison, those taking a placebo saw an overall 36 percent increase in IL-6 by the end of the study ... The current typical American diet contains between 15 and 17 times more omega-6 than omega-3, a ratio that researchers suggest should be lowered to 4-to-1, or even 2-to-1, to improve overall health"
- Omega-3 Heart Trial Fails the Test - vitalchoice.com, 6/15/12 - "Authors acknowledge their study's limitations and flaws ..."
- Why omega-3 oils help at the cellular level - Science Daily, 5/15/12 -"The scientists fed mouse macrophages -- a kind of white blood cell -- three different kinds of fatty acid: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (AA). EPA and DHA are major polyunsaturated omega-3 fatty acids, essential to a broad range of cellular and bodily functions, and the primary ingredient in commercial fish oil dietary supplements. AA is a polyunsaturated omega-6 fatty acid prevalent in the human diet ... They discovered that omega-3 fatty acids inhibit an enzyme called cyclooxygenase (COX), which produces the prostaglandin hormones that spark inflammation. The action is similar to what happens when one takes an aspirin, which disrupts the COX-2 signaling pathway, thus reducing inflammation and pain ... On the other hand ... omega-3 oils do not inhibit another group of enzymes called lipoxygenases (LOX), which are also produced by stimulated macrophages. One type of generated LOX enzyme in turn produces fat-signaling molecules called leukotrienes, which are pro-inflammatory. But Norris noted that LOX enzymes may also generate anti-inflammatory compounds called resolvins from EPA and DHA"
- Nutrition: More Omega-3, Less of a Suspect Protein - NYTimes.com, 5/7/12 -"Amyloid plaques and tangles in the brain are characteristic of Alzheimer’s disease and are known to increase the risk for mental decline ... higher levels of omega-3 intake were associated with significantly lower beta-amyloid blood levels"
- Eating fish, chicken, nuts may lower risk of Alzheimer's disease - Science Daily, 5/2/12 - "A new study suggests that eating foods that contain omega-3 fatty acids, such as fish, chicken, salad dressing and nuts, may be associated with lower blood levels of a protein related to Alzheimer's disease and memory problems ... 1,219 people older than age 65, free of dementia, provided information about their diet for an average of 1.2 years before their blood was tested for the beta-amyloid. Researchers looked specifically at 10 nutrients, including saturated fatty acids, omega-3 and omega-6 polyunsaturated fatty acids, mono-unsaturated fatty acid, vitamin E, vitamin C, beta-carotene, vitamin B12, folate and vitamin D ... the more omega-3 fatty acids a person took in, the lower their blood beta-amyloid levels. Consuming one gram of omega-3 per day (equal to approximately half a fillet of salmon per week) more than the average omega-3 consumed by people in the study is associated with 20 to 30 percent lower blood beta-amyloid levels ... Other nutrients were not associated with plasma beta-amyloid levels" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Fish oil added to yogurt may help consumers meet daily nutritional requirements - Science Daily, 3/28/12 - "In a preliminary study, tasters could not differentiate between low levels of fish and butter oils in unflavored yogurt, but they could discern yogurt flavored with oxidized fish oil, which has a strong fishy taste" - Hmmm!!! Fish flavored and chili and lime flavored yogurt. Try selling that idea. I'll stick to my fish oil capsules.
- Fatty diets may be associated with reduced semen quality - Science Daily, 3/14/12 - "The study of 99 men in the USA found an association between a high total fat intake and lower total sperm count and concentration. It also found that men who ate more omega-3 polyunsaturated fats (the type of fat often found in fish and plant oils) had better formed sperm than men who ate less ... if men make changes to their diets so as to reduce the amount of saturated fat they eat and increase their omega-3 intake, then this may not only improve their general health, but could improve their reproductive health too ... the relationship between dietary fats and semen quality was largely driven by the consumption of saturated fats. Men consuming the most saturated fats had a 35% lower total sperm count than men eating the least, and a 38% lower sperm concentration"
- Omega-3 reduces inflammatory marker to offer ‘multiple’ health benefits - Nutra USA, 3/2/12 - "The first of the two new studies ... indicated that omega-3 supplements were associated with reduced levels of sICAM-1, which may contribute to a decrease in the risk of atherosclerosis ... The second study ... indicated that increased levels of omega-3 may counteract the pro-carcinogenic action of sICAM-1" - [Abstract] [Abstract]
- Omega-3 Fatty Acids Help Brain Age Better - WebMD, 2/27/12 -"the results suggest diets lacking in omega-3 fatty acids may cause the brain to age faster ... people whose DHA levels were in the bottom 25% of the group had lower brain volumes compared with people with higher DHA levels ... In addition, people with both low DHA and all the other omega-3 fatty acid levels scored lower on tests of visual memory, processing, and abstract thinking ... Researchers say the results suggest that low DHA and other omega-3 fatty acid levels are associated with a pattern of memory and brain function problems even in people free of dementia"
- Omega-3s linked to slower eye sight loss in people with retinal disease: Study- Nutra USA, 2/14/12 - "people with the condition who consume at least 0.2 grams per day of omega-3 fatty acids have a 40% slower average annual rate of decline in distance visual acuity, compared with people with lower intakes"
- Study to determine whether fish oil can help prevent psychiatric disorders - Science Daily, 2/8/12 - "Researchers at Zucker Hillside Hospital's Recognition and Prevention (RAP) Program who have worked with teenagers at risk for serious mental illness for the past decade are now studying the effectiveness of Omega 3 fatty acids (fish oil) for treating psychiatric symptoms ... Of the 300 adolescents who have participated in the RAP Program, most have shown substantial improvement"
- Maternal omega-3 reduces eczema risk in children: Study - Nutra USA, 1/31/12 - "children whose mothers had consumed omega-3 daily had 36% less risk of developing eczema, a 38% reduction in the chance of being sensitised to egg, and 50% less chance of having egg allergy"
- Omega-3 may enhance benefits of strength training for the elderly - Nutra USA, 1/6/12 - "fish oil may be an attractive supplement for the elderly to maximize their neuromuscular responses to strength training, which is important to life quality" - [Abstract]
- Healthy oil components may fight pancreatitis - Nutra USA, 1/3/12 -"They found that the oleic acid and hydroxytyrosol – both of which are present in a particularly high concentration in virgin olive oil and omega-3 polyunsaturated fatty acids – offered protection from inflammatory damage from induced pancreatitis in pancreatic cells"
- Alzheimer's: Diet patterns may keep brain from shrinking - Science Daily, 12/29/11 - "People with diets high in several vitamins or in omega 3 fatty acids are less likely to have the brain shrinkage associated with Alzheimer's disease than people whose diets are not high in those nutrients ... Those with diets high in omega 3 fatty acids and in vitamins C, D, E and the B vitamins also had higher scores on mental thinking tests than people with diets low in those nutrients ... people with diets high in trans fats were more likely to have brain shrinkage and lower scores on the thinking and memory tests than people with diets low in trans fats"
- Possible cure for leukemia found in fish oil - Science Daily, 12/22/11 -"The compound -- delta-12-protaglandin J3, or D12-PGJ3 -- targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice ... The compound is produced from EPA -- Eicosapentaenoic Acid -- an Omega-3 fatty acid found in fish and in fish oil ... During the experiments, the researchers injected each mouse with about 600 nanograms of D12-PGJ3 each day for a week. Tests showed that the mice were completely cured of the disease. The blood count was normal, and the spleen returned to normal size. The disease did not relapse ... The researchers focused on D12-PGJ3 because it killed the leukemia stem cells, but had the least number of side effects"
- Some Fish Oil Supplements Fishy on Quality - WebMD, 12/7/11 -"None of the fish oil supplements contained contaminants, such as lead, mercury, or PCBs, that exceeded levels set by USP or the European Union ... the total PCB amounts in four brands (CVS Natural, GNC Triple Organic, Nature’s Bounty Odorless, and Sundown Naturals) were below the USP safe limit but within the range that would require a warning label under California’s Proposition 65, 90 parts per billion ... For the report, the consumer agency purchased three lots of 15 different top-selling brands of fish oil supplements online and in the New York metropolitan area ... Two of the three samples of Kirkland Signature Enteric 1200 fish oil supplements had an enteric coating (designed to prevent a fishy aftertaste) that did not disintegrate properly. The coating may break up in the stomach rather than in the small intestine, as desired for proper absorption by the body" - Note: So those bargains at Costco may not be such a bargain if they aren't absorbed.
- Young women may reduce heart disease risk eating fish with omega 3 fatty acids, study finds - Science Daily, 12/5/11 - "In the first population-based study in women of childbearing age, those who rarely or never ate fish had 50 percent more cardiovascular problems over eight years than those who ate fish regularly. Compared to women who ate fish high in omega-3 weekly, the risk was 90 percent higher for those who rarely or never ate fish ... Fish oil contains long chain omega-3 polyunsaturated fatty acids, which are believed to protect against heart and vascular disease. Few women in the study took fish oil supplements, so these were excluded from the analyses and the results were based on the dietary intake of omega-3 fatty acids, not intake from supplements"
- Eating fish can reduce the risk of diabetes - Science Daily, 11/11/11 -"the consumption of fish is associated with a decreased prevalence of diabetes and lower glucose concentrations whereas the consumption of red meat, especially cured meats is related to increased weight gain and obesity ... Eating red meat in excess is linked to higher cardiovascular risk, higher blood pressure, diabetes and a moderate decrease in life expectancy mainly due to cancer or heart disease. In contrast, fish appears in the Mediterranean diet and has health benefits for the heart"
- You are what you eat: Low fat diet with fish oil slows growth of human prostate cancer cells, study suggests - Science Daily, 10/25/11 - "Men who ate a low-fat diet with fish oil supplements for four to six weeks before having their prostate removed had slower cancer-cell growth in their prostate tissue than men who ate a traditional, high-fat Western diet ... The short-term study also found that blood obtained from patients after the low-fat, fish oil diet slowed the growth of prostate cancer cells in a test tube, while blood from men on the Western diet did not slow cancer growth ... Preclinical studies suggest that lowering dietary omega-6 fatty acids from corn oil and increasing omega-3 fatty acids from fish oil decreases the risk of prostate cancer development and progression," the study states. "We found this diet intervention resulted in a decrease in omega-6 vs. omega-3 fatty acid ratios in benign and malignant prostate tissue and a decrease in malignant cell proliferation"
- Boosting mental performance with fish oil? - Science Daily, 10/21/11 -"overall, taking either of two different types of fish oil supplement for three months had no consistent impact on mental function in 18 -- 35-year-olds, however they did find evidence of reduced mental fatigue and faster reaction times. Contrary to popular belief, these results suggest that taking omega-3 or fish oil supplements may not have an immediate or measureable impact on mental performance in healthy young adults, possibly due to the fact that this population is already performing at its mental peak or that higher doses or longer than 12 weeks supplementation are required ... Interestingly, in the second of these studies it was found that taking DHA-rich fish oil over the same time period did increase blood flow to active areas of the brain during performance of similar mental tasks. The researchers claim these findings could have implications for mental function later on in life, as evidence suggests regularly eating oily fish or taking omega-3 supplements may prevent cognitive decline and dementia, and increased blood flow to the brain may be a mechanism by which this occurs"
- Omega-3 fatty acids shown to prevent or slow progression of osteoarthritis - Science Daily, 10/17/11 - "New research has shown for the first time that omega-3 in fish oil could "substantially and significantly" reduce the signs and symptoms of osteoarthritis ... omega-3-rich diets fed to guinea pigs, which naturally develop osteoarthritis, reduced disease by 50 per cent compared to a standard diet ... Furthermore, there was strong evidence that omega-3 influences the biochemistry of the disease, and therefore not only helps prevent disease, but also slows its progression, potentially controlling established osteoarthritis ... The only way of being certain that the effects of omega-3 are as applicable to humans as demonstrated in guinea pigs is to apply omega-3 to humans. However, osteoarthritis in guinea pigs is perhaps the most appropriate model for spontaneous, naturally occurring osteoarthritis, and all of the evidence supports the use of omega-3 in human disease ... Most diets in the developed world are lacking in omega-3, with modern diets having up to 30 times too much omega-6 and too little omega-3. Taking omega-3 will help redress this imbalance and may positively contribute to a range of other health problems such as heart disease and colitis"
- Omega-3 may ease depression symptoms, slash dementia risk: RCT - Nutra USA, 9/23/11 - "recruited 50 people over the age of 65 to participate in their six-month double-blind, randomized controlled trial ... Participants received daily supplements of EPA- or DHA-rich fish oil, or the omega-6 linoleic acid (LA, 2.2 grams per day). The EPA-rich supplement provided 1.67 grams of EPA and 0.16 grams of DHA, while the DHA-rich supplement provided 1.55 grams of DHA and 0.40 grams of EPA ... compared with the group receiving the LA supplements, the EPA-rich supplement group displayed higher scores on the Geriatric Depression Scale ... On the other hand, the DHA group displayed improvements in verbal fluency ... These results indicate that DHA-rich and EPA-rich fish oils may be effective for depressive symptoms and health parameters, exerting variable effects on cognitive and physical outcomes" - [Abstract]
- Omega-3 supplements show benefits against anxiety: Human data - Nutra USA, 9/14/11 - "the Ohio State researchers recruited 68 medical students to participate in their parallel group, placebo-controlled, double-blind trial. The med students were given either placebo capsules or omega-3 capsules containing 2085 mg of EPA (eicosapentaenoic acid) and 348 mg DHA (docosahexanoic acid) ... Results showed a 14% reduction in levels of the production of pro-inflammatory interleukin 6 (IL-6), as well as a 20% reduction in anxiety symptoms in the omega-3 group, compared to the placebo group ... Proinflammatory cytokines promote secretion of corticotropin-releasing hormone (CRH), a primary gateway to hormonal stress responses; CRH also stimulates the amygdala, a key brain region for fear and anxiety. Accordingly, alterations in inflammation could also influence anxiety" - [Abstract] - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com. Note: CRH increases cortisol. See:
- Maternal omega-3 intake may influence childhood allergy - Nutra USA, 9/12/11 - "Omega-3 fatty acids may aid the development of the infant gut and improve how gut immune cells respond to bacteria and foreign substances, making the baby less likely to suffer from allergies in the long term, according to new research in pigs ... These findings suggest that feeding fatty acids of the omega-3 family during pregnancy and lactation impact newborn intestinal barrier function ... such changes “are likely to reduce the risk of developing allergies in later life" ... The end result is that the baby's immune system may develop and mature faster – leading to better immune function and less likelihood of suffering allergies ... the pig intestine is an excellent model of the human gut, however, so they are hopeful that the findings can be extrapolated" - [Abstract]
- Omega-3 Effective for Treating Child ADHD - Medscape, 9/8/11 - "In an evaluation of 10 trials with 699 total children with ADHD, investigators found that those who received omega-3 supplements had a "small but significant" improvement in symptom severity compared with those who were given placebo. This effect was also significant in the children who received supplements that specifically contained higher doses of eicosapentaenoic acid ... Omega-3 supplements that included higher doses of eicosapentaenoic acid were also significantly associated with lowering ADHD symptoms ... There were no significant differences found for any dose of docosahexaenoic acid or α-linolenic acid, or between omega-3 monotherapy vs augmenting traditional ADHD medications with omega-3" - See Mega Twin EPA at Amazon.com.
- Marine, but not plant, omega-3s may boost heart health for women: Study - Nutra USA, 9/7/11 - "High intakes of long chain omega-3 eicosapentaenoic acid (EPA, C20:5 n-3) and docosahexaenoic acid (DHA, C22:6 n-3) was associated with a 38% reduction in the risk of ischemic heart disease (IHD) in women, but not men ... Much attention has been paid to the conversion of ALA to the longer chain EPA, with many stating that this conversion is very small. Indeed, between 8 and 20 per cent of ALA is reportedly converted to EPA in humans, and between 0.5 and 9 per cent of ALA is converted to DHA ... high intakes of long chain omega-3s ranging from 0.45 to 11.2 grams per day were associated with a 38% reduction in IHD risk for women only" - [Abstract]
- Fish oil's impact on cognition and brain structure identified in new study - Science Daily, 8/17/11 - "Researchers at Rhode Island Hospital's Alzheimer's Disease and Memory Disorders Center have found positive associations between fish oil supplements and cognitive functioning as well as differences in brain structure between users and non-users of fish oil supplements ... compared to non-users, use of fish oil supplements was associated with better cognitive functioning during the study. However, this association was significant only in those individuals who had a normal baseline cognitive function and in individuals who tested negative for a genetic risk factor for Alzheimer's Disease known as APOE4. This is consistent with previous research ... The unique finding, however, is that there was a clear association between fish oil supplements and brain volume ... In other words, fish oil use was associated with less brain shrinkage in patients taking these supplements during the ADNI study compared to those who didn't report using them"
- Omega-3 Supplements May Lower Anxiety - Medscape, 7/22/11 - "In a small randomized controlled trial of medical students, those who received omega-3 supplements for 3 months showed a 20% reduction in anxiety scores and a 14% reduction in stimulated interleukin 6 (IL-6) production ... Chronic inflammation has been linked to a broad spectrum of health problems, including cardiovascular disease, stroke, and rheumatoid arthritis ... A total of 68 first- and second-year medical students (56% male; mean age, 23.65 years) were enrolled and randomized to receive 3 times daily either omega-3 supplement capsules (consisting of 2085 mg of EPA and 348 mg of DHA, n = 34) or fish-flavored placebo capsules (n = 34) for 12 weeks ... We chose the 7:1 EPA/DHA balance because of evidence that EPA has relatively stronger anti-inflammatory and antidepressant effects than DHA"
- Earlier the better for omega-3 benefits for brains & hearts? - Nutra USA, 7/4/11 - "the older animals did benefit from fish oil supplementation, but the benefits were limited to diastolic function, or the filling of the heart with blood following contraction (systolic) ... The younger animals had better spatial memory than the older animals, and the fish oil supplements were not associated with any reversal of the age-related memory deficits or increases in inflammation in the brain, wrote the researchers" - [Abstract]
- DHA and EPA Have Differential Effects on LDL-Cholesterol - Medscape, 5/22/11 -"EPA inhibited lipid hydroperoxide (LOOH) formation by 42% and 54% in vesicles with normal and elevated cholesterol levels, respectively. DHA, on the other hand, inhibited LOOH by 28% in vesicles with elevated cholesterol levels only. The separate effects of EPA, DHA, and EPA/DHA were enhanced when used in combination with statin therapy, including atorvastatin, atorvastatin metabolite, simvastatin, or rosuvastatin. The most potent antioxidant capacity was observed with EPA and the active metabolite of atorvastatin"
- Heart failure risk lower in women who often eat baked/broiled fish - Science Daily, 5/24/11 - "In a large-scale analysis, women who ate the most baked/broiled fish (five or more servings/week) had a 30 percent lower risk of heart failure compared to women who seldom ate it (less than one serving/month) ... dark fish (salmon, mackerel and bluefish) were associated with a significantly greater risk reduction than either tuna or white fish (sole, snapper and cod) ... eating fried fish was associated with increased heart failure risk. Even one serving a week was associated with a 48 percent higher heart failure risk"
- Omega-3 may reduce depression symptoms in the elderly: Study - Nutra USA, 5/18/11 - "According to findings published in The Journal of Nutrition, Health & Aging, depressed women who received daily supplements containing 2.5 grams of omega-3 experienced significant reductions in their symptoms ... In addition, researchers from the University of Pavia also report that omega-3 supplements providing a daily EPA (eicosapentaenoic acid) dose of 1.67 grams and a daily DHA (docosahexaenoic acid) dose of 0.83 grams reported improvements in the ‘quality of life’" - [Abstract] - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
- Fish oil boosts responses to breast cancer drug tamoxifen, researchers find - Science Daily, 4/6/11 - "omega-3 fatty acids -- abundant in fish -- could be a safe and beneficial booster for tamoxifen therapy ... [in rats] Omega-3 fatty acids produced a greater expression of genes related to cellular specialization, or differentiation -- a sign of lower cancer severity -- compared to corn oil. The combination of fish oil and tamoxifen reduced the expression of genes linked to tumor growth and spreading ... If a tumor was being treated with tamoxifen, the addition of an omega-3 fatty acid diet seemed to make the tumor, at least at the molecular level, more benign and less aggressive and responsive to tamoxifen"
- Eskimo study suggests high consumption of omega-3s in fish-rich diet reduces obesity-related disease risk - Science Daily, 3/24/11 -"A study of Yup'ik Eskimos in Alaska, who on average consume 20 times more omega-3 fats from fish than people in the lower 48 states, suggests that a high intake of these fats helps prevent obesity-related chronic diseases such as diabetes and heart disease ... The fats the researchers were interested in measuring were those