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Posted: 2/21/2012 10:52:23 PM
Chondroitin is a dietary supplement used to
treat arthritis and heart disease.
- Other names for Chondroitin include: CDS,
CSC, and CSA.
Dosage: There are many doses for this
medicine. The most common doses for Chondroitin are listed below. Ask your
doctor if your health problem is not on the list or if the dose is not
given for a product you want to use.
- Arthritis, capsules or tablets: 800 to
1200 milligrams daily, by mouth (1,2,3)
- Heart disease, capsules or tablets:
1.5 to 10 grams daily, by mouth (4)
Summary 2: Super Nutrition, Vancouver
Since so many people over age 50 have some
painful joints, we assume it’s just a part of growing older. Research
shows that it need not be so. There are reasons why joints break down and
ways to slow or even reverse the process.
- Cartilage, the very smooth substance that
caps the ends of the bones, consists of water - 65 to 80% - collagen,
chondrocytes and proteoglycans. Jason Theodosakis’ excellent description
of how cartilage works: "To get an idea of what cartilage does,
imagine rubbing together two perfectly flat, smooth, slightly wet ice
cubes. They glide across each other quickly and easily, never catching or
slowing. Now imagine a surface that’s five to eight times more slippery
than ice. That’s your cartilage, the material that makes it possible for
the ends of your bones to slide smoothly and easily across each other. In
fact, no man-made substance can compare to the low-friction and
shock-absorbing properties of health cartilage." (Jason Theodosakis,
M.D. The Arthritis Cure: the medical miracle that can halt, reverse and
may even cure osteoarthritis. St. Martin’s Press. New York. 1997.)
- A number of factors - especially trauma
to the mobile joints - interfere with the careful synthesis of these
ingredients that causes cartilage to break down. The result is sore, stiff
joints with limited movement. Once smooth and slippery, cartilage now
becomes thin and uneven, with bones painfully rubbing together.
- Chondroitin sulfate is a natural
substance found in cartilage where it performs several important functions
that keep cartilage healthy. A bit like a magnet, chondroitin attracts
precious water, including nutrient-rich fluid into the cartilage. Not
enough water in cartilage can cause dryness, pain and loss of nutrients in
- Sometimes the body produces too many
enzymes that ‘cut up’ connective tissue, acting as thousands of tiny
scissors. Besides attracting fluid into dry cartilage, chondroitin
inhibits the work of degradative enzymes that hasten cartilage
destruction. Chondroitin stimulates the production of key components of
cartilage, such as the chondrocytes and proteoglycans. It works well with
glucosamine to rebuild damaged cartilage.
- As it naturally occurs in the body
already, it is an extremely safe substance. People who took large amounts
of chondroitin - 1.5 to 10 grams a day - for six years showed no ill
Summary 3: Bodybuilding.com - Boise,
1. What is it and where does it come from?
Chondroitin sulfate is one of the major constituents of cartilage. Animal
studies indicate that chondroitin sulfate promotes the healing of bone. It
has also been shown to help restore joint function in people with
osteoarthritis. In addition, chondroitin sulfate may reduce the risk of
atherosclerosis and heart attacks, as well as help prevent kidney stones.
- Chondroitin sulfate consists of
repeating chains of molecules called mucopolysaccharides. It is a primary
part of cartilage. Classified as a type of glycosaminoglycan, chondroitin
sulfate is rich in sulfur and is a relative of glucosamine.
Animal cartilage is the only significant food source of Chondroitin
2. What does it do and what scientific studies give evidence
to support this?
Not only does chondroitin provide structure and holds water and nutrients,
but it allows other molecules to move through cartilage. This is a very
important property, as there is no blood supply to cartilage. As a result,
joint healing is greatly increased through supplementation. Chondroitin
and similar compounds are also exist in the bladder and lining of blood
vessels. Here they help to prevent abnormal movement of blood, urine, or
components across the barrier of the vessel or bladder wall.
- Japanese researchers have found that Chondroitin sulfate in synovial
fluid collected from the temporomandibular joint provides a useful
indicator of the degree of damage there, and that chondroitin may play a
role in determining the viscosity and elasticity of tissues and fluids. A
recent in vitro study done by scientists in Belgium found that chondroitin
had potentially beneficial effects on human cartilage cells.
3. Who needs it and what are some symptoms of deficiency?
Because the body makes chondroitin, the possibility of a dietary
deficiency is uncertain.
A daily requirement has not been set.
sulfate may be used to rebuild and repair joint cartilage affected by
osteoarthritis and possibly other forms of arthritis.
4. How much should be taken? Are there any side effects?
For atherosclerosis, researchers have used very high amounts, such as 5
grams twice per day with meals, lowering the amount to 500 mg three times
per day after a couple of months. However, before taking such high
amounts, people should consult a nutritionally oriented doctor. For
osteoarthritis, the typical level is 400 mg three times per day.
Chondroitin is often combined with the similar arthritis-relieving
Chondroitin may also be combined with vitamin
C. Most products potency ranges from 400 to 600 mg. Nausea might occur
at intakes greater than 10 grams per day. No other adverse side-effects
have been reported.